Makes me wonder...hey OP did you happen to start magically fouling plugs coinciding with a change in fuel octane or brand? Perhaps is E10 to blame?
How about the switch from summer to winter blends playing a role? Is your pickup in otherwise good running condition or are the valve guides beat?
Does it smoke on start up?
It makes sense to seek a "hotter" range of plug or a stronger spark but that won't fix a broken valve guide. Heat range really is about degrees of camshaft timing and operating range.
Spark plugs are how to
tune engines, not repair them.
What other changes happened before you bought a new distributor and why did you think that would fix it? Are you certain that it is installed and adjusted correctly? How do you know?
In my experiences as an auto mechanic lots of light can be shed by looking into the past
especially when the owner has popped the hood with tools in hand. Nothing personal old boy but I only report facts. So let's have em.
There ain't no good reason to start fouling plugs out of the blue, there are some other factor(s) in play. Something else changed beside the distributor we haven't looked at.
Got a valve tap? Been messin with the rocker nuts? Swap intake manifolds lately?
What kind of oil are you using and is it overdue for change?