My truck has Hedman headers w/ flowmasters, dumps behind rear wheel wells out to the sides. Collectors back 2.5" tube. Drivers side window down, 65mph in OD, the left bank exhaust is predominate. Not a fan of the sound.
Had a 99 C2500 quad cab short bed w/350 Vortec stock exhaust two into one 90 series Flowmaster, 2.25" inlets & 2.5" outlet, out the rider side ahead of rear wheel and it sounded perfect. Throaty, sweet rumble at idle, and all business in passing gear. Loved it.
I don't remember the 76 BBC square I owned (76-81) sounding like this one. (my 79)
Bottom line:
I'd go headers, make the muffler the virual "ypipe". Two large inlets and one out large as possible and dump as soon as you can get it pass the cab, front of rear wheel, or 45 to the ground. Through the bed side looks cool to me. Just my two cents.