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Under the seat are drain plugs in the floor. I would sacrifice one of those. Otherwise the only other real hole is by the brake booster and bulk head connector, that wouldn't be very convenient though.
You can reuse the wiring hole for the hvac wiring going from the cab to the blower motor. GM used a big grommet down to a small bundle of wiring. You can order a new grommet in the same outside diameter with a larger inside diameter to add your Amp wiring to the existing blower motor wiring routing.