If your 383 build is full tilt and you get your set up to hook your 10 bolt wont be long for this world , imo.
If you are in it to win it with a bad boy motor and trans. I would find a 12 bolt and put your money into that and scrap the 10 bolt. If you just spin the tires everywhere your 10 bolt should last.
Gears depend on a lot of things , what tranny you have , tire size , cam profile and how often you will drive it down the hwy at 65/70 mph. 4.11,s are a pretty good set up for drag racing and ok on the hwy. if you have a 700r od trans. and a large tire in the back ,(like a 32" mickey ) but not so good on the hwy. with a non od trans. with a low prfile , (50 series) rear tire , maybe 3.73's would be more street friendly. It all depends on your motor and what you want to do.
As far as a spool they are totally do able on the street , but you will scrub off your tires , screech them when you turn into a parking space and a spool is not corner friendly. There is a lot of good posi"s that work well for drag racing that are street friendly too , thats the way I would go. I ran a moroso super brute with red springs in a 12 bolt and it worked great for both street and drag racing and there is a lot of others to choose from as well. You dont really need to go with a locker or a spool in a street machine unless your are just stuck on that.
Also ring and pinions are like chevy vs. ford everybody has there own opinion but I have had good luck with yukon gear and motive gear , (they are pretty much all made in china now) but some are better than others , (dont go cheapo) , I myself would not buy richmond , but thats just me.
Go get a 12 bolt you will be happier in the long run ,IMO