I did the LS thing a few years ago and it's by far the best thing you can do to these trucks. Here's what sticks out to me:
- A) Pick a better cam. That cam sucks in a heavy truck. My buddy's got it in a suburban and my god is it a dog.
- B) The 706 heads are a good choice to bump compression. They won't hurt flow (unless you're turning it 7500+ and then any OE head is going to be limited)
- C) The only way to know for sure if your cam will work with the heads/not have PTV issues is to check PTV yourself. You can also talk to Texas Speed and they can give you a rough yay or nay but the only way to know for sure is to check it yourself
- D) That AR-5 isn't going to last long if you plan to beat on it. Drive it nice and hopefully never hook up, with a good clutch and you'll be ok. I have a Vengeance Clutch dual disc in mine with a T56 and it's awesome
- E) Stock truck manifolds don't clear the frame. Get headers or the Hooker manifolds
- F) You should already be drive by wire being an '06 engine. The TBSS intake is a good power bump on any LS
- G) You lost me on the computer side. I used the donor Envoy E40 computer that came with my engine and my buddy/tuner tuned it with HP.
For the suspension, you're going down a rabbit hole nobody else has been. Also, there are literal thousands of 5x5 wheels, there's no benefit whatsoever to go to 6-lug. Most 6-lug guys with the older trucks convert to 5-lug. Also, that 2000 Silverado rear end won't have the correct mounting pads or anything to mate up to your leafs most likely. Not to mention it'll have the GM "Gov-Loc" that is not at all desirable (it's called a Gov-bomb for a reason) and a terrible rear disc design that never works well. I would highly suggest just using your original 10-bolt and building it up (I did mine with 30-spline stuff from Quick Performance that should be good through 6-700hp) or pick up a 9-inch from QP that's set up for these trucks.
I'm running a ~425hp 5.3 (LH6 with flat top pistons, ~10.2:1 compression, 799 heads, TBSS intake) with a TSP Bald Eagle N/A cam, T56 Magnum with a Vengeance Clutch dual disc, 4" custom driveshaft and the original 10-bolt built as stated above with 3.90 gears and a Yukon Duragrip posi unit. Got 41k on everything but the trans swap, almost 15k on the T56 setup. Regular drop spindles, cut springs up front, flip kit and a shackle in the back for a ~5/8 drop. The only thing I don't like about my setup is I need more gear (going 4.30) and it wheel hops real bad so it needs traction bars (but I have TCI full pro-touring suspension to go on it). Otherwise it's a riot