Whole front end rebuild at 95k miles, everything was completely worn out (had a balljoint fail and found everything else). Granted, it's had a 2" level most of it's 71k miles before I bought it and then I threw on a 3" but I've had several NBS trucks that were cranked to the moon with their original front end components with 150-200k miles on them. Wheel bearings both went about the same time too. Level kits on these don't put anything at weird angles like older trucks either, I'm completely at a loss as to why everything was worn out at such a low mileage.
Parking brake design is STUPID. It has cables that pull an L-bracket that goes through the backing plates. This L-bracket/pivot seizes over time from corrosion and there's no way to avoid it. Mine has never worked, gotta pull the axles out to replace everything. Just about everybody on the forums or IRL that I know with one of these have never had a working parking brake, even down south.
Not to mention the Hemi tick/lifter failures. LS's have them too, just as often. But after I'd bought the truck and was doing research, I found how bad a of a design the 5.7 Hemi is. The cam being raised so far in the block and a main oil galley being between it and the crank, blocking 90% of the oil splash it would traditionally get, was a bad idea IMO. Granted, my truck has no tick/lifter issues or anything, it runs like a scalded dog. It'll make a little noise on startup if it sits for a couple weeks straight but so do 100% of any vehicle with hydraulic lifters. I specifically looked for a '16+ truck cuz they seem to have fewer issues in this area. Oh and the oil filter location is stupid too, right above the front crossmember and EPAS rack.
Speaking of that rack, it's very common for them to just randomly fail and then it's $3500-up for a replacement. My GF had a '13 Ram and had to pay $4500 to get hers replaced by a shop.
The 8hp is awesome overall, especially paired with the 3.92s mine has. My only real gripe with it is that if you don't come to a complete stop and pause, it tries to start off in 2nd and feels like it's slipping till it goes down into first. It'll also do that in 3rd/2nd occasionally. That could be fixed with a tune though.
Oh yeah, the computer is encrypted too. So you have to send it off to be unlocked, which is like $400, before you can spend $7-900 to have it tuned. And the trans computer is a separate computer that also has to be unlocked and then tuned separately. So it's like $1500 to tune one of these things.
The reverse camera/radio will randomly be dark when I go to put it in reverse and I can't see anything. The heated seats also will randomly have days where they only work for a few minutes rather than till you turn them off. I've checked the grids and wiring and found no issues, seems to just be a random gremlin in both these cases.
This being a Daimler/Mercedes/semi-German designed product, it's just nature of the beast. It's a great truck if you keep up on everything. But I quite literally have worked on this truck more than my '85 over the past year and I'm over it.