I definitely don't have the max horsepower goal that most folks have for their 350. My truck is a 2nd/extra vehicle that I've had for the last 16 years, and I like to keep it looking good, but very functional. It looks good, and works very well as a truck whenever I need it.
My engine was originally a GM crate 350/290 HP engine ( a very mismatched compression/cam combination), and it worked well for a while. Then I swapped in a milder cam because I hoped it would improve the mixture enough to get a little better gas mileage. Mild cam was very smooth, but no real difference in mileage. I always used high ZDDP synthetic oil with the flat tappet cam
I decided I now want more performance, but to also keep the engine very usable in a truck. For performance potential, all the original GM iron heads have severe limitations, even the famed camel hump heads, so I wanted aluminum heads or Vortec iron. Even though I have 4.10 gears and stock 31" tires, the truck has a lot of mass to get moving, and I want torque to come in low so that it "feels" strong all the time. Using a cam with duration up in the high 20's or even 30-35 duration would have worked with these heads, but probably would not have improved torque in the low rpm range. I also wanted to keep stock pistons, which limited compression to about 9.4 with 64cc heads, and most high duration cams need more compression to work well. I want power/torque to come in low and stay even, and the cam I chose has those characteristics. I think this cam/head/compression combination is a good match for what I want.
The reason I spent more money than necessary on a roller cam is that its my hobby. I've looked at this stuff for years, but this was the time to try it out. I also wanted a really reliable engine, and the roller cam and full roller rockers should give me a low friction combination that holds up really well. I don't plan to rev it that high very often, so the extra valve train weight should not be an issue.
I estimate my current setup is running about 330 HP, limited by my stock exhaust manifolds and mufflers. If I swap in long tube headers and 2 1/2" pipes I should be at about 350-360 HP, and all that power will come in early and have a flat torque curve.
In retrospect, I should have looked harder at the Blueprint Vortec 350 crate with roller cam for $2,600. I could have just dropped it in, added a Vortec intake, and saved a lot of time hanging over the engine compartment working on my engine.
Bruce